Hoãn
| Crystal Palace | 3 - 0 | Arsenal |
| Sociedad | 1 - 0 | Espanyol |
| AC Milan | 0 - 0 | Bologna |
| L.R. Vicenza Virtus | 20:00 | Crotone |
| Monza | 20:00 | Ascoli Calcio 1898 FC |
| Nancy | 0 - 2 | AC Ajaccio |
| FC Porto | 3 - 0 | Santa Clara |
| Varzim | 2 - 1 | FC Porto B |
| Hatayspor | 0 - 0 | Adana Demirspor |
| Istanbul Basaksehir | 1 - 0 | Yeni Malatyaspor |
| Leganes | 3 - 2 | Fuenlabrada |
| Cerezo Osaka | 0 - 1 | Kashiwa Reysol |
| Suwon Bluewings | 0 - 1 | Jeonbuk FC |
| Daegu FC | 1 - 2 | Incheon United |
| Jeju United | 1 - 2 | Ulsan Hyundai |
| Kaizer Chiefs | 22:00 | TS Galaxy |
| SuperSport United | 22:00 | Chippa United |
| SuperSport United | 1 - 1 | Chippa United |
| Jong AZ Alkmaar | 0 - 1 | Roda JC Kerkrade |
| Jong Ajax | 4 - 1 | đứng top Oss |
| Jong FC Utrecht | 1 - 0 | NAC Breda |
| Jong PSV | 2 - 2 | FC Volendam |
| Jeonnam Dragons | 0 - 1 | Daejeon Citizen |
| Bucheon FC 1995 | 0 - 0 | Seoul E-Land FC |
| Hamburger SV | 4 - 0 | Erzgebirge Aue |
| Quảng nam | 1 - 0 | tỉnh bình dương |
| tp. Hà tĩnh | 3 - 2 | nam Định |
| Sarawak United | 1 - 1 | Pulau Pinang |
| Melaka United | 0 - 1 | Sabah FA |
| Negeri Sembilan | 2 - 2 | Selangor |
| Curico Unido | 0 - 0 | Palestino |
| Barnechea | 0 - 1 | Union San Felipe |
| Universidad de Concepcion | 2 - 2 | CD Arturo Fernandez Vial |
| Afrin SC | 0 - 3 | Jableh SC |
| Al-Horgelah | 0 - 3 | Al-Ittihad |
| Al-Nawaeir | 2 - 3 | Al-Futowa |
| Al-Shorta | 0 - 4 | Al-Jaish |
| Al-Wathbah | 0 - 0 | Tishreen |
| Hutteen | 1 - 0 | Al-Karamah |
| Central Coast Mariners | 5 - 0 | Wellington Phoenix |
| Cortulua | 0 - 1 | Deportivo Pasto |
| Once Caldas | 0 - 1 | Bucaramanga |
| PFC Lokomotiv Sofia 1929 | 2 - 1 | FC Tsarsko Selo Sofia năm ngoái |
| Alashkert FC | 20:00 | Noravank |
| BKMA | 20:00 | Ararat |
| Pyunik | 20:00 Dừng | Sevan |
| Universitario de Deportes | 2 - 1 | Asociacion Deportiva Tarma |
| FK MAS Taborsko | 1 - 0 | Sparta Prague B |
| SK Prostejov | 2 - 2 | MFk Vyskov |
| 2 de Mayo | 0 - 2 | Sportivo San Lorenzo |
| Sportivo Trinidense | 1 - 0 | Guarani de Trinidad |
| Elfsborg | 0 - 2 | Mjaellby |
| Djurgaarden | 3 - 1 | Degerfors |
| IK Brage | 3 - 0 | Orebro SK |
| Landskrona BoIS | 1 - 3 | Oesters IF |
| FC STK 1914 Samorin | 1 - 1 | Zeleziarne Podbrezova |
| UCD | 0 - 2 | Derry đô thị |
| Finn Harps | 2 - 2 | Drogheda United |
| Treaty United | 2 - 0 | Athlone Town |
| Resovia | 1 - 1 | Stomil Olsztyn |
| Sandecja Nowy Sacz | 2 - 0 | GKS Jastrzebie |
| Olimpia Grudziadz | 0 - 3 | Lech Poznan |
